Table 3.

Bivariate and multivariable linear regression analyses examining the association between gender affirmation and mental health symptoms in a U.S. sample of transgender adults (N = 288)

	Depressive symptoms						Anxiety symptoms						Stress symptoms
	Model 4A						Model 5A						Model 6A
	Bivariate			Multivariable			Bivariate			Multivariable			Bivariate			Multivariable
	Beta	SE	p Value	aBeta	SE	p Value	Beta	SE	p Value	aBeta	SE	p Value	Beta	SE	p Value	aBeta	SE	p Value
Social: disclosure of gender identity
No	Ref		–	Ref	–	–	Ref	–	–	Ref	–	–	Ref	–	–	Ref	–	–
Yes	−13.40	5.31	.01	−15.31	5.14	.003	−5.54	4.44	0.21	−8.49	4.18	.04	−7.52	4.72	.11	−9.63	4.49	.03
Medical: hormone use
No	Ref		–	Ref	–	–	Ref	–	–	Ref	–	–	Ref	–	–	Ref	–	–
Yes	−4.21	1.32	.002	−2.54	1.36	.06	−1.69	1.11	0.13	−0.34	1.10	.76	−4.05	1.16	<.001	−2.67	1.19	.02
Medical: gender affirmation procedures
No	Ref		–	Ref	–	–	Ref	–	–	Ref	–	–	Ref	–	–	Ref	–	–
Yes	−5.02	1.32	<.001	−3.85	1.40	.01	−3.67	1.10	0.001	−3.03	1.14	.01	−4.45	1.17	<.001	−3.07	1.22	.01
	Model 4B						Model 5B						Model 6B
	Multivariable			Multivariable			Multivariable			Multivariable			Multivariable			Multivariable
	Beta	SE	p Value	aBeta	SE	p Value	Beta	SE	p Value	aBeta	SE	p Value	Beta	SE	p Value	aBeta	SE	p Value
Number of gender affirmation experiences	−3.67	0.78	<.001	−3.48	0.79	<.001	−2.07	0.66	.002	−1.82	0.64	.01	−3.27	0.69	<.001	−3.04	0.69	<.001

SE standard error; aBeta adjusted beta. Multivariable models adjusted for age, education, and transgender-related discrimination experiences. Bolded p-values = significant at p < 0.05; italicized p-values = approaching significance (p = 0.05)