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. Author manuscript; available in PMC: 2021 Sep 15.
Published in final edited form as: Acc Chem Res. 2020 Aug 12;53(9):1869–1880. doi: 10.1021/acs.accounts.0c00323

Figure 6.

Figure 6.

Radioactive nanomedicines for renal function diagnosis. (a) Porphyrin-PEG mesh showed delayed excretion in mice with acute kidney injury (AKI). Adapted with permission from Ref.25. Copyright (2016) Elsevier. (b) PET imaging of POM clusters in healthy mice and mice with early or end stage of UUO. (c) Kidney kinetics of POM clusters guided the differentiation of UUO at the early and late stage. (d) UUO kidney at the early stage showed strong uptake of POM clusters, while at the end stage, no uptake was observed. Panel b-d adapted with permission from Ref.26. Copyright (2018) Elsevier.