Figure 7. Mortality after exposure to isoflurane increases with age in heterozygous ND2360114 flies.
ND2360114/wild-type flies of the indicated ages were exposed to 2h of 2% isoflurane in 75% O2, and the percent mortality at 24 h was determined. Each experiment consisted of four biological replicates. Symbols indicate the following: box (Q2-Q3), + (mean), horizontal bar (median), and whiskers (minimum and maximum). Significance was determined using an ordinary one-way ANOVA followed by the Dunnett post-hoc test for multiple comparisons. **, P<0.01; ****, P<0.0001.