Table 7.
Scores on the Modified Mini-Mental State Exam (mMMS) and the Columbia University Autobiographical Memory Interview-Short Form (CUAMI-SF) for the Mode 1 Only and Mode 2 Samples Across Assessment Time Points in the Optimization of ECT (OPT-ECT) Study
| Mode 2 Sample |
|||||||
|---|---|---|---|---|---|---|---|
| Mode 1 Only | Mode 2 Sample | P-Value* | 6 x ST RUL | 1.5 x ST BL | P-Value* | ||
| mMMS | |||||||
| Pre-ECT | Mean | 50.10 | 48,31 | 0.11 | 47.00 | 49.62 | 0.29 |
| SD | 6.79 | 8,87 | 8.88 | 8.84 | |||
| N | 226 | 52 | 26 | 26 | |||
| Post Mode 1 | Mean | 47.29 | 47.77 | 0.63 | 46.86 | 48.97 | 0.22 |
| SD | 7.10 | 6.10 | 6.65 | 5.24 | |||
| N | 181 | 52 | 29 | 23 | |||
| Two-Month Follow-up | Mean | 51.54 | 51.38 | 0.89 | 50.00 | 52.75 | 0.19 |
| SD | 5.50 | 5.01 | 5.56 | 4.18 | |||
| N | 112 | 24 | 12 | 12 | |||
| Six-Month Follow-up | Mean | 51.69 | 52.63 | 0.35 | 51.55 | 53.53 | 0.29 |
| SD | 4.48 | 4.33 | 5.30 | 3.26 | |||
| N | 98 | 24 | 11 | 13 | |||
| CUAMI Consistency Score | |||||||
| Post Mode 1 | Mean | 59.27 | 56.86 | 0.46 | 56.28 | 55.22 | 0.90 |
| SD | 20.16 | 18.29 | 20.33 | 16.06 | |||
| N | 178 | 18 | 11 | 7 | |||
| Post Mode 2 | Mean | 49.43 | 51.24 | 47.75 | 0.60 | ||
| SD | 16.16 | 15.08 | 17.54 | ||||
| N | 25 | 12 | 13 | ||||
| Two-Month Follow-up | Mean | 67.09 | 54.75 | 0.005 | 53.01 | 57.03 | 0.60 |
| SD | 15.41 | 18.18 | 20.43 | 15.52 | |||
| N | 105 | 23 | 13 | 10 | |||
| Six-Month Follow-up | Mean | 68.44 | 59.40 | 0.02 | 57.57 | 61.23 | 0.59 |
| SD | 15.96 | 15.26 | 18.92 | 11.13 | |||
| N | 97 | 22 | 11 | 11 | |||
BL, Bilateral; RUL, Right Unilateral; ST, seizure threshold
*
P-values reflect independent t-tests comparing the Mode 1 only and Mode 2 samples or the Mode 2 sample as a function of the randomized Mode 1 treatment assignment.