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Blood pressure and heart rate. a Systolic blood pressure, b diastolic blood pressure, c mean blood pressure, d heart rate. No statistically significant differences or biologically relevant differences in the blood pressure (systolic, diastolic and mean blood pressures), heart rate, and electrocardiogram parameters were noted in animals dosed at 250, 500, and 1000 mg/kg at any measuring time point when compared to the control values
