. 2020 Mar 3;36(4):343–357. doi: 10.1007/s43188-019-00036-y

Table 5.

Effect of α-lipoic acid (LA) on oxidative stress parameters in the testis and epididymis of controls and linuron-exposed rats

Tissue	Groups	Controls	LA	Linuron		Linuron ± LA
Tissue	Parameters	Controls	LA	10 mg/Kg	50 mg/Kg	10 mg/Kg	50 mg/Kg
Testis	SOD	17.28^a ± 1.41	16.42^a ± 1.54	10.07^b ± 1.32	8.57^b ± 1.08	13.08^d ± 1.97	13.58^d ± 1.11
	CAT	11.48^a ± 1.08	12.38^a ± 1.52	7.75^b ± 0.93	5.67^c ± 0.76	10.66^d ± 0.34	9.65^d ± 0.47
	GR	4.012^a ± 0.075	4.11^b ± 0.092	3.82^c ± 0.021	1.86^d ± 0.045	3.72^e ± 0.063	2.64^f ± 0.077
	GPx	3.12^a ± 0.026	3.09^a ± 0.083	2.97^b ± 0.033	0.98^c ± 0.067	3.05^a ± 0.052	2.39^d ± 0.034
	GSH	14.54^a ± 1.72	15.63^a ± 2.27	14.28^a ± 1.72	7.28^b ± 1.24	15.72^a ± 1.35	11.28^c ± 1.23
	LPx	11.48^a ± 2.55	10.67^a ± 1.78	20.21^b ± 3.65	27.12^c ± 2.64	16.98^d ± 1.21	19.08^d ± 2.13
	PC’s	2.04^a ± 0.28	2.73^b ± 0.11	5.63^c ± 0.26	6.01^c ± 0.48	3.21^d ± 0.34	3.48^d ± 0.17
Cauda epididymis	SOD	19.18^a ± 2.02	20.27^a ± 1.18	8.71^b ± 0.64	9.27^c,b ± 1.02	16.42^d ± 1.24	13.18^e ± 0.47
	CAT	7.23^a ± 0.26	8.01^b ± 0.88	4.27^c ± 0.17	3.18^d ± 0.23	6.21^e ± 0.19	5.98^e ± 0.21
	GR	5.07^a ± 0.025	4.97^b ± 0.064	3.28^c ± 0.042	2.53^d ± 0.061	4.01^e ± 0.038	3.56^f ± 0.011
	GPx	3.25^a ± 0.063	3.29^a ± 0.041	2.32^b ± 0.085	1.34^c ± 0.091	2.76^d ± 0.021	2.83^d ± 0.038
	GSH	10.18^a ± 0.79	12.31^b ± 0.28	5.72^c ± 0.39	4.49^d ± 0.27	8.65^e ± 0.17	7.27^f ± 0.12
	LPx	12.34^a ± 1.07	13.18^a ± 1.36	26.21^b ± 2.47	27.18^b ± 3.68	18.07^c ± 1.03	20.98^d ± 1.39
	PC’s	1.98^a ± 0.27	2.01^a ± 0.39	5.99^b ± 0.25	6.08^b ± 0.47	3.08^c ± 0.17	3.12^c ± 0.53

Data are expressed as mean ± SD of 10 individual rats

SOD Superoxide dismutase (Units/mg protein), CAT Catalase (μmoles of H₂O₂ decomposed/mg protein/min), GSH Reduced glutathione (μmol of thiourea/mg protein/h), LPx Lipid peroxidation (μmol of malondialdehyde formed/g tissue), PC Protein carbonyl content (nmol carbonyl/mg protein), GR Glutathione reductase (µmol of NADPH oxidized/mg protein/min), GPx Glutathione peroxidase (µmol of NADPH oxidized/mg protein/min)

^a–fDifferent superscripts in the same row indicate a significant difference (p<0.05)