Table 4.
Potential prognostic factors for patient outcome by univariate and multivariate COX regression analysis.
| Variable | Univariable analysis (N = 60) | Multivariable analysis (N = 60) | ||
|---|---|---|---|---|
| P-value | HR (95% CI) | P-value | HR (95% CI) | |
| Gender (female) | 0.461 | 0.552 (0.113, 2.684) | - | - |
| Age | 0.028 | 1.054 (1.006, 1.105) | 0.080 | 1.046 (0.995, 1.099) |
| Hematuria (0 = none; 1 = microscopic; 2 = macroscopic) | 0.634 | 1.291 (0.451, 3.695) | - | - |
| Proteinuria (0 = none; 1 = non-nephrotic; 2 = nephrotic) | 0.773 | 0.850 (0.281, 2.568) | - | - |
| SCr on diagnosis (increased by 200 μmol/L) | 0.457 | 1.207 (0.735, 1.981) | - | - |
| Serum C3 (increased by 0.1 g/L) (n = 52) | 0.057 | 2.010 (0.980, 4.120) | - | - |
| Kidney IgG staining >1+ | 0.894 | 1.101 (0.267, 4.533) | - | - |
| IgG deposit on TBM and/or Bowman's capsule | 0.377 | 2.032 (0.422, 9.797) | - | - |
| Kidney C3 staining intensity (increased by 1+) | 0.012 | 1.937 (1.155, 3.248) | 0.263 | 1.664 (0.682, 4.060) |
| Kidney C1q positive staining | 0.710 | 1.347 (0.279, 6.500) | - | - |
| Percentage of crescents (increased by 10%) | 0.016 | 1.272 (1.045, 1.547) | 0.173 | 1.156 (0.938, 1.425) |
| Combined with other GN | 0.755 | 0.811 (0.217, 3.030) | - | - |
| ACEIs/ARBs | 0.191 | 0.351 (0.073, 1.688) | - | - |
| Steroids | 0.140 | 3.269 (0.679, 15.741) | - | - |
| Cytotoxic drugs | 0.812 | 1.183 (0.296, 4.735) | - | - |
| Plasmapheresis | 0.628 | 1.673 (0.209, 13.396) | - | - |
Bold values represent P < 0.05.