TABLE 6.
Serum and liver tissue levels of TC, TG, HDL-c and LDL-c in mice.
Group (serum) | TC (mmol/L) | TG (mmol/L) | HDL-c (mmol/L) | LDL-c (mmol/L) |
Normal | 1.82 ± 0.03f | 0.11 ± 0.02e | 1.55 ± 0.11a | 0.31 ± 0.06f |
Control | 5.49 ± 0.11a | 1.08 ± 0.12a | 0.26 ± 0.05e | 1.48 ± 0.14a |
L-carnitine | 2.66 ± 0.09d | 0.48 ± 0.06c | 0.92 ± 0.05c | 0.51 ± 0.04d |
LF-CQPC04-L | 3.63 ± 0.10c | 0.74 ± 0.05b | 0.56 ± 0.04d | 0.70 ± 0.05c |
LF-CQPC04-H | 2.25 ± 0.12e | 0.32 ± 0.03d | 1.18 ± 0.07b | 0.40 ± 0.03e |
LB | 4.02 ± 0.08b | 0.77 ± 0.04b | 0.51 ± 0.07d | 0.93 ± 0.08b |
Group (liver tissue) | TG (mmol/gprot) | TC (mmol/gprot) | HDL-c (mmol/gprot) | LDL-c (mmol/gprot) |
Normal | 4.41 ± 2.20f | 72.83 ± 5.41f | 65.21 ± 3.36a | 0.42 ± 0.04f |
Control | 126.52 ± 8.71a | 292.33 ± 16.12a | 7.21 ± 1.08f | 2.67 ± 0.21a |
L-carnitine | 33.25 ± 4.82d | 162.34 ± 16.03d | 36.25 ± 3.69c | 0.92 ± 0.11d |
LF-CQPC04-L | 45.89 ± 6.33c | 206.36 ± 19.32c | 25.16 ± 4.08d | 1.30 ± 0.12c |
LF-CQPC04-H | 19.78 ± 3.31e | 126.71 ± 15.20e | 48.32 ± 4.42b | 0.68 ± 0.06e |
LB | 68.21 ± 7.82b | 241.08 ± 21.35b | 15.52 ± 2.81e | 1.72 ± 0.09b |
Values presented are the mean ± standard deviation (n = 10/group). a–fMean values with different letters in the same column are significantly different (P < 0.05) according to Duncan’s multiple range test. LF-CQPC04-L: mice treated with a low concentration of Lactobacillus fermentum CQPC04 (1.0 × 108 CFU/kg); LF-CQPC04-H: mice treated with a high concentration of Lactobacillus fermentum CQPC04 (1.0 × 109 CFU/kg); LB: Mice treated with Lactobacillus delbrueckii subsp. Bulgaricus (1.0 × 109 CFU/kg).