Table 4.

Summary characteristics of studies comparing confirmed TBM with non-TBM.

References	Country	Continent	TB burden*	Study design	Samples	TBM/non-TBM patients recruited	PBMCs or CSFMCs/well	Test results
								TP	FP	FN	TN
Park et al. (31)	Korea	Asia	Intermediate	Prospective	Peripheral blood	17/57	2.5 × 105	14	24	3	33
					Cerebrospinal fluid	17/57	2.5 × 105	14	12	3	45
Park et al. (41)	Korea	Asia	Intermediate	Prospective	Peripheral blood	28/159	2.5 × 105	27	66	1	93
					Cerebrospinal fluid	22/109	2.5 × 105	19	16	3	93
Pan et al. (46)	China	Asia	High	Prospective	Peripheral blood	21/37	2.5 × 105	20	6	1	31
					Cerebrospinal fluid	21/36	1 × 105 -2.5 × 105	13	1	8	35

^*Refer to Global Tuberculosis Report 2019; TB, tuberculosis; TBM, tuberculous meningitis; PBMCs, peripheral blood mononuclear cells; CSFMCs, cerebrospinal fluid mononuclear cells; TP, true positive; FP, false positive; FN, false negative; TN, true negative.