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. 2020 Sep 3;8:469. doi: 10.3389/fped.2020.00469

Table 4.

Micronutrient deficiency rates in ASD and typically developing children in Chongqing and Hainan.

Micronutrients ASD-Chongqing TD-Chongqing ASD-Hainan TD-Hainan P
Zinc 7.64 (34) 0.5 (1)a*** 1 (3)c*** 0 (0) <0.001
Ferritin 15.7 (70) 16.9 (34) 4.1 (12)c*** 2 (2) <0.001
Folate 0.2 (1) 0 (0) 0.3 (1) 0 (0) 1.000
Vitamin B12 0 (0) 0 (0) 0 (0) 0 (0)
Vitamin D deficiency 8.8 (39) 4 (8)a* 1.7 (5)c*** 1 (1) <0.001
inadequacy 49.7 (221) 59.4 (119)a* 18.4 (54) 2 (2)b***
Vitamin A deficiency 38.4 (171) 21.4 (43)a*** 13.7 (40)c*** 7.9 (8) <0.001
marginal deficiency 46.7 (208) 41.3 (83) 36.9 (108)c* 45.5 (46)

Data shown as percentage (number). Chi-square test, and Fisher's exact test were used in the analysis.

a

Significant difference of percentage of micronutrient deficiency of autism children compared with typically developing children in Chongqing.

b

Significant difference of percentage of micronutrient deficiency of autism children compared with typically developing children in Hainan province.

c

Significant difference of percentage of micronutrient deficiency of autism children in Chongqing compared with autism children in Hainan province.

P-value was adjusted in multiple comparisons by the Bonferroni method.

*

P < 0.05,

***

P < 0.001.

ASD, autism spectrum disorder; TD, typically developing.