TABLE 1.
Summary of 4CMenB antigen sequence characterization for MenB strains in Finlanda
| CC | ST | fHbp variant |
fHbp peptide |
NHBA peptide |
NadA peptide |
PorA_VR2 | No. of isolates |
|---|---|---|---|---|---|---|---|
| ST-162 complex | 10538 | 3 | 31 | 20 | X | 15 | 2 |
| ST-174 complex | 2272 | 1 | 4 | 9 | X | 9 | 1 |
| ST-213 complex | 213 | 3 | 45 | 18 | X | 14 | 1 |
| ST-213 complex | 213 | 3 | 45 | 1341 | X | 14 | 1 |
| ST-213 complex | 213 | 3 | 45 | 29 | X | 14 | 1 |
| ST-213 complex | 213 | 3 | 45 | 1057 | X | 14 | 1 |
| ST-213 complex | 213 | 3 | 882 | 18 | X | 14 | 1 |
| ST-213 complex | 213 | 3 | 187 | 637 | X | 14 | 1 |
| ST-213 complex | 13348 | 3 | 45 | 1342 | X | 14 | 1 |
| ST-269 complex | 269 | 1 | 15 | 21 | X | 2-2 | 1 |
| ST-269 complex | 2693 | 1 | 15 | 21 | X | 13-1 | 1 |
| ST-269 complex | 479 | 1 | 15 | 21 | X | 13-1 | 1 |
| ST-269 complex | 10943 | 2 | 19 | 1058 | X | 13 | 1 |
| ST-32 complex/ET-5 complex | 32 | 1 | 883 | 3 | 1 | 16-6 | 1 |
| ST-32 complex/ET-5 complex | 32 | 1 | 1 | 3 | 1 | 16 | 1 |
| ST-364 complex | 7523 | 1 | 2 | 635 | X | 13-1 | 1 |
| ST-41/44 complex | 41 | 1 | 4 | 2 | X | 4 | 1 |
| ST-41/44 complex | 41 | 1 | 14 | 2 | X | 10-7 | 1 |
| ST-41/44 complex | 41 | 1 | 14 | 894 | X | 10-7 | 1 |
| ST-41/44 complex | 303 | 1 | 14 | 2 | X | 4 | 3 |
| ST-41/44 complex | 303 | 1 | 14 | 2 | X | 16-3 | 1 |
| ST-41/44 complex | 13978 | 1 | 13 | 1344 | 1 | 13-1 | 1 |
| ST-41/44 complex/lineage 3 | 41 | 1 | 4 | 2 | X | 9 | 1 |
| ST-41/44 complex/lineage 3 | 41 | 1 | 4 | 2 | X | 4 | 1 |
| ST-41/44 complex/lineage 3 | 41 | 1 | 14 | 2 | X | 10-7 | 1 |
| ST-41/44 complex/lineage 3 | 41 | 1 | 14 | 129 | X | 1 | 1 |
| ST-41/44 complex/lineage 3 | 303 | 1 | 14 | 2 | X | 4 | 16 |
| ST-41/44 complex/lineage 3 | 303 | 1 | 14 | 1056 | X | 4 | 1 |
| ST-41/44 complex/lineage 3 | 207 | 2 | 19 | 1055 | X | 14-6 | 1 |
| ST-41/44 complex/lineage 3 | 207 | 2 | 19 | 43 | X | 14-6 | 3 |
| ST-41/44 complex/lineage 3 | 7516 | 1 | 525 | 266 | X | 13-4 | 1 |
| ST-41/44 complex/lineage 3 | 8091 | NA (chimera) | 207 | 892 | X | 28 | 1 |
| ST-41/44 complex/lineage 3 | 2247 | 1 | 14 | 2 | X | 10-7 | 1 |
| ST-41/44 complex/lineage 3 | 154 | 1 | 4 | 10 | X | 4 | 1 |
| ST-41/44 complex/lineage 3 | 11915 | 2 | 19 | 2 | X | 15-1 | 1 |
| ST-41/44 complex/lineage 3 | 44 | 1 | 8 | 2 | X | 26 | 1 |
| ST-41/44 complex/lineage 3 | 136 | 2 | 24 | 10 | X | 16-3 | 1 |
| ST-41/44 complex/lineage 3 | 2314 | 1 | 4 | 31 | X | 4 | 1 |
| ST-41/44 complex/lineage 3 | 1732 | 1 | 110 | 894 | X | 25-11 | 1 |
| ST-60 complex | 4146 | 1 | 13 | 24 | X | 2 | 1 |
| NA | NA | 1 | 13 | 20 | X | 14 | 1 |
| NA | NA | 3 | 31 | 20 | X | 15 | 1 |
| Singlet | 1572 | 1 | 13 | 20 | X | 14 | 6 |
| Singlet | 1572 | 1 | 13 | 20 | X | 10-1 | 1 |
| Singlet | 1572 | 1 | 13 | 1343 | X | 14 | 1 |
| Singlet | 10184 | 1 | 14 | 21 | X | 14-6 | 1 |
| Singlet | 11515 | 1 | 260 | 20 | X | 14 | 1 |
| Singlet | 2271 | 1 | 135 | 46 | X | 10-2 | 1 |
| Singlet | 2793 | NA | Contig border | 893 | X | 34 | 1 |
| Singlet | 2793 | 1 | 4 | 893 | X | 34 | 2 |
| Singlet | 2793 | 1 | 4 | 893 | X | 2-2 | 1 |
| Singlet | 11916 | 1 | 4 | 664 | X | 1 | 1 |
| Singlet | 9390 | 2 | 24 | 6 | X | 1 | 1 |
| Singlet | 2265 | 1 | 4 | 893 | X | 14 | 1 |
| Singlet | 10942 | 2 | 106 | 21 | X | 3 | 1 |
a
Abbreviations: 4CMenB, multicomponent meningococcal B vaccine; CC, clonal complex; ST, sequence type; fHbp, factor H-binding protein; NHBA, neisserial heparin binding antigen; NadA, Neisseria adhesin A; PorA, porin A; VR, variable region; NA, not available.