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. 2020 Sep 16;10:15154. doi: 10.1038/s41598-020-72082-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Proton pump inhibitor treatment response for typical gastroesophageal reflux diseases. At week four, the complete and partial response rates for heartburn were 54.5% and 23.6%, respectively, and the complete and partial response rates for regurgitation were 50.9% and 34.5%, respectively. After PPI treatment for eight weeks, the complete response tended to increase for both heartburn and regurgitation compared to those at week four. PPI, proton pump inhibitor.