Table 1.
Baseline characteristics of included patients.
| Variable | All patients | Patients with biologic marker and microbial data |
|---|---|---|
| N | 55 | 18 |
| Age, year, mean ± SD | 56.1 ± 15.3 | 56.8 ± 15.1 |
| Sex, n (%) | ||
| Male | 23 (41.8) | 10 (55.6) |
| Female | 32 (58.2) | 8 (44.4) |
| BMI, mean ± SD | 24.6 ± 3.8 | 22.8 ± 2.7 |
| Obesity (BMI ≥ 25), n (%) | 21 (38.2) | 3 (16.7) |
| Smoking habit, n (%) | ||
| Never smoker | 40 (72.7) | 12 (66.7) |
| Former smoker | 9 (16.4) | 3 (16.7) |
| Current smoker | 6 (10.9) | 3 (16.7) |
| Alcohol consumption, n (%) | ||
| Never consumption | 29 (52.7) | 6 (33.3) |
| Former consumption | 3 (5.5) | 3 (16.7) |
| Current consumption | 23 (41.8) | 9 (50.0) |
| Comorbidity, n (%) | ||
| Hypertension | 10 (18.2) | 2 (11.1) |
| Diabetes mellitus | 5 (9.1) | 0 (0.0) |
| Old cerebrovascular accident | 2 (3.6) | 0 (0.0) |
| Arrythmia | 1 (1.8) | 0 (0.0) |
| Other cardiac disease | 3 (5.5) | 0 (0.0) |
| Dyslipidemia | 11 (20.0) | 4 (22.2) |
| Fatty liver | 2 (3.6) | 1 (5.6) |
| History of malignant disease | 2 (3.6) | 0 (0.0) |
| Heartburn | ||
| Frequency, /week, mean ± SD | 4.8 ± 4.5 | 18.4 ± 27.4 |
| Duration, month, mean ± SD | 22.5 ± 58.2 | 5.7 ± 4.6 |
| Regurgitation | ||
| Frequency, /week, mean ± SD | 3.6 ± 3.4 | 22.1 ± 36.5 |
| Duration, month, mean ± SD | 23.6 ± 59.8 | 5.2 ± 4.4 |
BMI, body mass index; SD, standard deviation.