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. 2020 Sep 16;11(9):763. doi: 10.1038/s41419-020-02945-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Chondrocytes were cultured with IL-4/IL-13-induced M2 macrophages with indicated transfections. a RT-qPCR and western blot experiments for the SOX9 mRNA and protein levels in chondrocytes of each group. b Levels of Acan, Col2a1, and Col1a1 in chondrocytes of each group. c, d The production of sGAG and Collagen II in chondrocytes of each group. **P < 0.01. The error bar expressed as mean ± SD of three independent experiments in triplicates.