Table 1.
Change in the proportion and cell size of fast blue-labelled trigeminal neuronal cells with or without substance P-immunoreactivity following benzalkonium chloride-induced ocular surface inflammation.
| Observed samples | Total number of FB-labelled cells | Number (%) of FB-labelled cells with SP-IR | Cell size of FB-labelled cells with SP-IR (μm2, mean ± SD) | Cell size of FB-labelled cells without SP-IR (μm2, mean ± SD) | |
|---|---|---|---|---|---|
| Control | 6 | 99 | 26 (26.3%) | 309.1 ± 109.5 | 322.0 ± 89.1 |
| BAK | 6 | 144 | 70 (48.6%)* | 415.6 ± 262.9† | 327.2 ± 198.2 |
| 1 week | 6 | 144 | 68 (47.2%)* | 494.5 ± 343.8† | 298.1 ± 137.1 |
| 2 months | 6 | 72 | 30 (41.7%)* | 518.7 ± 307.5† | 311.8 ± 208.9 |
BAK benzalkonium chloride, FB fast blue, SP-IR substance P-immunoreactivity, SD standard deviation.
*Significant difference compared to the control group by Chi-square test (P < 0.05).
†Significant difference compared to the control group by Dunn’s multiple comparison test as a post-hoc test of non-parametric ANOVA test (P < 0.05).