Table 4.

Correlations of VLCFA and blood lipid levels.

	C22:0	C24:0	C26:0	Ratio C24:0/C22:0	Ratio C26:0/C22:0
total cholesterol	p < 0.001 rs = 0.638; n = 92	p < 0.001 rs = 0.521; n = 92	p < 0.001 rs = 0.365; n = 92	p = 0.023 rs = 0.237; n = 92	p = 0.067 rs = 0.192; n = 92
LDL	p < 0.001 rs = 0.521; n = 89	p < 0.001 rs = 0.548; n = 89	p < 0.001 rs = 0.415; n = 89	p = 0.004 rs = 0.305; n = 89	p = 0.013 rs = 0.262; n = 89
HDL	p = 0.085 rs = 0.183; n = 89	p = 0.470 rs = 0.077; n = 89	p = 0.712 rs = -0.040; n = 89	p = 0.682 rs = 0.044; n = 89	p = 0.342 rs = -0.102; n = 89
TG	p = 0.001 rs = 0.341; n = 90	p = 0.060 rs = 0.199; n = 90	p = 0.359 rs = 0.098; n = 90	p = 0.744 rs = 0.035; n = 90	p = 0.800 rs = 0.027; n = 90

Bivariate correlations were analyzed using Spearman's correlation coefficient due to the non-Gaussian distributed very long chain fatty acids values, TG, and HDL. A 2-tailed significance level of p < 0.002 was considered to be statistically significant (highlighted in bold), which was calculated using Bonferroni correction (total of 25 correlations analyzed—including mutation types as described in the “Results” section).

HDL: high-density lipoproteins; LDL: low-density lipoproteins; TG: triglycerides.