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. 2020 Sep 3;11:1235. doi: 10.3389/fphar.2020.01235

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Copyright © 2020 Huang, Li, Zeng, Chen, Wei, Liu and Qi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of Ang II (A, D), CCN2 (B, E), and CCN5 (C, F) concentrations in different of blood pressure levels among hypertensive patients with or without ACEI. Data were expressed as median with interquartile range (IQR); whiskers represent ± 1.5 IQR (boxplots). ^* P < 0.05 vs. control, ^# P < 0.05 vs. grade 1, ^$ P < 0.05 vs. grade 2. ^†P < 0.05 vs. No ACEI. grade 1/2/3 were defined as the grade of blood pressure in hypertensive patients. Ang II, angiotensin II; CCN2, cellular communication network factor 2; CCN5, cellular communication network 5; ACEI, angiotensin converting enzyme inhibitor.