Table 1.

Younger cohort aged 6–7 years at baseline, older cohort aged 12–13 years at baseline: Summary data on sample size, time intervals from baseline, rate of follow up, age, gender, ocular biometrics and spherical equivalent refractive error. AL, axial length, CR, corneal radius, AL/CR, axial length to corneal radius ratio, ACD, anterior chamber depth, SER, spherical equivalent refractive error, SD, standard deviation, IQR, inter-quartile range.

Younger cohort
	Baseline	Phase 2	Phase 3	Phase 4
Time from baseline (years) (IQR)		+ 3.00 (2.97–3.03)	+ 6.10 (5.85–6.16)	+ 9.05 (8.98–9.10)
Sample size	390	295	211	125
Rate of follow up (%)		76	54	32
% male	49.5	46.8	49.3	52.8
Mean age (years) ± SD	7.07 ± 0.38	10.07 ± 0.41	13.08 ± 0.35	16.01 ± 0.36
Median AL (mm) (IQR)	22.56 (22.02–23.07)	23.08 (22.53–23.59)	23.36 (22.82–23.88)	23.65 (23.12–24.26)
Median CR (mm) (IQR)	7.82 (7.63–8.00)	7.82 (7.65–8.02)	7.81 (7.68–8.04)	7.84 (7.70–8.06)
Median AL/CR ratio (IQR)	2.89 (2.83–2.94)	2.95 (2.89–3.01)	2.98 (2.93–3.04)	3.00 (2.93–3.08)
Median ACD (mm) (IQR)	3.45 (3.33–3.59)	3.58 (3.43–3.71)	3.63 (3.49–3.78)	3.70 (3.52–3.85)
SER (D) (IQR)	+ 1.13 (+ 0.63 to + 1.75)	+ 0.75 (+ 0.25 to + 1.25)	+ 0.75 (+ 0.25 to + 1.25)	+ 0.68 (-0.25 to + 1.13)

Older cohort
	Baseline	Phase 2	Phase 3	Phase 4
Time from baseline (years) (IQR)		+ 2.97 (2.88–2.99)	+ 6.04 (+ 5.81–6.18)	+ 8.92 (8.86–9.00)
Sample size	657	427	225	113
Rate of follow up (%)		65	34	17
% male	50.5	45.0	43.1	36.3
Mean age (years) ± SD	13.09 ± 0.36	16.05 ± 0.32	19.20 ± 0.42	21.98 ± 0.35
Median AL (mm) (IQR)	23.30 (22.71–23.91)	23.44 (22.84–24.09)	23.47 (22.84–24.19)	23.69 (23.04–24.54)
Median CR (mm) (IQR)	7.92 (7.73–8.08)	7.93 (7.75–8.09)	7.90 (7.74–8.08)	7.98 (7.73–8.14)
Median AL/CR ratio (IQR)	2.97 (2.92–3.03)	2.98 (2.93–3.05)	3.00 (2.93–3.05)	3.01 (2.94–3.07)
Median ACD (mm) (IQR)	3.62 (3.47–3.78)	3.67 (3.48–3.84)	3.65 (3.51–3.83)	3.68 (3.51–3.88)
SER (D) (IQR)	+ 0.50 (+ 0.00 to + 1.13)	+ 0.50 (-0.13 to + 1.13)	+ 0.75 (-0.13 to + 1.50)	+ 0.69 (-0.25 to + 1.38)