Figure 6.

Antiangiogenesis Therapeutic Effects of iRGD-exo-AntagomiRs in Xenograft Mouse Models of NPC

(A) Excised tumors collected from each group. (B–D) Body weights (B), tumor volume (C) and weights of tumor (D) were calculated for each group. All bars and error bars stand for mean values and the corresponding SEM. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001). (E) The expression of CD31, which represents MVD in tumor sections of HONE1-EBV xenografts of tumor. Original magnification, ×200. (F) H&E staining of major organs following antiangiogenesis therapy of iRGD-exo-antagomiRs in NPC xenograft mouse models (n = 5).