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. 2020 Sep 3;10:1560. doi: 10.3389/fonc.2020.01560

Table 2.

Tumor characteristics of patients with COVID-19 pneumonia.

Variables All
n = 70
<14% extent
n = 38
14–30% extent
n = 23
≥30% extent
n = 9
P-value
Cancer 0.83
    Breast 27 (38%) 17 (45%) 7 (30%) 3 (34%)
    Lung 11 (16%) 6 (16%) 5 (22%) 0 (0%)
    Hemopathy 5 (7%) 2 (5%) 2 (9%) 1 (11%)
    Gynecologic 6 (9%) 4 (10%) 1 (4%) 1 (11%)
    GI 9 (13%) 3 (8%) 4 (17.5%) 2 (22%)
    Others 12 (17%) 6 (16%) 4 (17.5%) 2 (22%)
PS 0.26
    <2 43 (61%) 27 (71%) 12 (52%) 4 (44%)
   ≥2 27 (39%) 11 (29%) 11 (48%) 5 (56%)
Stage 0.99
    Local 22 (31%) 12 (32%) 7 (30%) 3 (33%)
    Metastatic 48 (69%) 26 (68%) 16 (70%) 6 (67%)
Metastatic site
    Lung 17/48 (35%) 9/26 (35%) 5/16 (31%) 3/6 (50%) 0.71
    Brain 8/48 (17%) 4/26 (15%) 4/16 (25%) 0/6 (0%) 0.36
    Liver 14/48 (29%) 5/26 (19%) 7/16 (44%) 2/6 (33%) 0.23
    Bone 20/48 (42%) 10/26 (39%) 5/16 (31%) 4/6 (67%) 0.31
    Peritoneum 5/48 (10%) 2/26 (8%) 1/16 (6%) 2/6 (33%) 0.14
Number of lines of treatment 0.23
    <3 41/48 (85%) 24/26 (92%) 13/16 (81%) 4/6 (67%)
   ≥3 7/48 (15%) 2/26 (8%) 3/16 (19%) 2/6 (33%)
Oncologic treatment
    Surgery 1 (1%) 1 (3%) 0 (0%) 0 (0%) 0.65
    Chemotherapy 27 (39%) 14 (37%) 10 (44%) 3 (33%) 0.74
    Targeted or endocrine therapies 12 (17%) 10 (26%) 2 (9%) 0 (0%) 0.07
    Immunotherapy 3 (4%) 2 (5%) 1 (4%) 0 (0%) 0.78
    Radiotherapy 2 (3%) 1 (3%) 0 (0%) 1 (11%) 0.24
Regular treatment
    Corticosteroids 18 (26%) 9 (24%) 6 (26%) 3 (33%) 0.59
    NSAID 3 (4%) 2 (5%) 1.0 (4%) 0 (0%) 0.52
    Anticoagulants 8 (11%) 1 (3%) 6 (26%) 1 (11%) 0.02

Data are expressed as n (%). Corticosteroids refer to a chronic daily dose equivalent to ≥10 mg of prednisolone (chemotherapy premedication was not taken into account); PS, performance status; NSAID, non-steroidal anti-inflammatory drugs.

Bold p-values were considered statistically significant (p < 0.05).