Table 2.
Tumor characteristics of patients with COVID-19 pneumonia.
Variables |
All n = 70 |
<14% extent n = 38 |
14–30% extent n = 23 |
≥30% extent n = 9 |
P-value |
---|---|---|---|---|---|
Cancer | 0.83 | ||||
Breast | 27 (38%) | 17 (45%) | 7 (30%) | 3 (34%) | |
Lung | 11 (16%) | 6 (16%) | 5 (22%) | 0 (0%) | |
Hemopathy | 5 (7%) | 2 (5%) | 2 (9%) | 1 (11%) | |
Gynecologic | 6 (9%) | 4 (10%) | 1 (4%) | 1 (11%) | |
GI | 9 (13%) | 3 (8%) | 4 (17.5%) | 2 (22%) | |
Others | 12 (17%) | 6 (16%) | 4 (17.5%) | 2 (22%) | |
PS | 0.26 | ||||
<2 | 43 (61%) | 27 (71%) | 12 (52%) | 4 (44%) | |
≥2 | 27 (39%) | 11 (29%) | 11 (48%) | 5 (56%) | |
Stage | 0.99 | ||||
Local | 22 (31%) | 12 (32%) | 7 (30%) | 3 (33%) | |
Metastatic | 48 (69%) | 26 (68%) | 16 (70%) | 6 (67%) | |
Metastatic site | |||||
Lung | 17/48 (35%) | 9/26 (35%) | 5/16 (31%) | 3/6 (50%) | 0.71 |
Brain | 8/48 (17%) | 4/26 (15%) | 4/16 (25%) | 0/6 (0%) | 0.36 |
Liver | 14/48 (29%) | 5/26 (19%) | 7/16 (44%) | 2/6 (33%) | 0.23 |
Bone | 20/48 (42%) | 10/26 (39%) | 5/16 (31%) | 4/6 (67%) | 0.31 |
Peritoneum | 5/48 (10%) | 2/26 (8%) | 1/16 (6%) | 2/6 (33%) | 0.14 |
Number of lines of treatment | 0.23 | ||||
<3 | 41/48 (85%) | 24/26 (92%) | 13/16 (81%) | 4/6 (67%) | |
≥3 | 7/48 (15%) | 2/26 (8%) | 3/16 (19%) | 2/6 (33%) | |
Oncologic treatment | |||||
Surgery | 1 (1%) | 1 (3%) | 0 (0%) | 0 (0%) | 0.65 |
Chemotherapy | 27 (39%) | 14 (37%) | 10 (44%) | 3 (33%) | 0.74 |
Targeted or endocrine therapies | 12 (17%) | 10 (26%) | 2 (9%) | 0 (0%) | 0.07 |
Immunotherapy | 3 (4%) | 2 (5%) | 1 (4%) | 0 (0%) | 0.78 |
Radiotherapy | 2 (3%) | 1 (3%) | 0 (0%) | 1 (11%) | 0.24 |
Regular treatment | |||||
Corticosteroids | 18 (26%) | 9 (24%) | 6 (26%) | 3 (33%) | 0.59 |
NSAID | 3 (4%) | 2 (5%) | 1.0 (4%) | 0 (0%) | 0.52 |
Anticoagulants | 8 (11%) | 1 (3%) | 6 (26%) | 1 (11%) | 0.02 |
Data are expressed as n (%). Corticosteroids refer to a chronic daily dose equivalent to ≥10 mg of prednisolone (chemotherapy premedication was not taken into account); PS, performance status; NSAID, non-steroidal anti-inflammatory drugs.
Bold p-values were considered statistically significant (p < 0.05).