Table 2. PITX1 gene expression analysis in different clinical parameters of breast cancer with Bc-GenExMiner v4.3.
| Variables | No. of patients | PITX1 mRNA | P value* |
|---|---|---|---|
| Age | 0.3119 | ||
| ≤51 | 2730 | – | |
| >51 | 4605 | – | |
| ER | <0.0001 | ||
| Negative | 2366 | Increased | |
| Positive | 6534 | – | |
| PR | – | 0.1186 | |
| Negative | 1559 | – | |
| Positive | 2159 | – | |
| HER-2 | 0.0188 | ||
| Negative | 2389 | – | |
| Positive | 438 | Increased | |
| Nodal status | <0.0001 | ||
| Negative | 4150 | – | |
| Positive | 3225 | Increased | |
| Triple-negative status | 0.0013 | ||
| Non-triple-negative | 6834 | – | |
| Triple-negative | 573 | Increased | |
| Basal-like status | <0.0001 | ||
| Non-basal-like | 7496 | – | |
| Basal-like | 1958 | Increased |
*
Statistical significance was determined by the Welch’s test.