Table 2. GO and KEGG pathway enrichment analysis of DEGs in the most significant module.
| Term | Pathway description | Count | P-value |
|---|---|---|---|
| GO:0006996 | Organelle organization | 6 | 7.28E-05 |
| GO:0000280 | Nuclear division | 5 | 5.88E-07 |
| GO:0022402 | Cell cycle process | 5 | 5.62E-06 |
| GO:0043229 | Intracellular organelle | 6 | 0.0219599139512363 |
| GO:0043234 | Protein complex | 5 | 0.00510417758391666 |
| GO:0005694 | Chromosome | 4 | 5.31E-04 |
| GO:1901363 | Heterocyclic compound binding | 6 | 0.00719682984698825 |
| GO:0032559 | Adenyl ribonucleotide binding | 5 | 5.57E-04 |
| GO:0016887 | ATPase activity | 3 | 0.00687545528482454 |
| hsa05168 | Herpes simplex virus one infection | 15 | 0.000113535 |
| hsa01212 | Fatty acid metabolism | 19 | 0.000206574 |
| hsa03013 | RNA transport | 10 | 0.000466728 |
Abbreviations: GO, Gene Ontology; DEG, differentially expressed gene; KEGG, Kyoto Encyclopedia of Genes and Genomes; PAH, pulmonary arterial hypertension.