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. 2020 Sep 16;40(9):BSR20201696. doi: 10.1042/BSR20201696

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© 2020 The Author(s).

This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY).

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The maximum of the first differentiation of left ventricular pressure (LV +dP/dt_max) and decline (LV -dP/dt_max) and left ventricle systolic pressure (LVSP) were reduced, and LV end-diastolic pressure (LVEDP) was increased in MI-induced heart failure rats, and these changes were further aggravated by miR-132 antagomiR treatment. The results are expressed as mean ± SE; N=8; *P<0.05 versus the Sham+NC antagomiR group; ^#P<0.05 versus the MI+NC antagomiR group.