Figure 2.

Depletion of Peripheral Helper ILC and Cytotoxic NK Cell Subsets in Treatment-Naive HIV-Infected Pediatric Subjects

(A) CD4 percentage of CD45⁺ lymphocytes (left) and plasma viral load (right) of pediatric HIV-uninfected (HIV⁻) subjects (n = 25), pediatric slow progressors (PSPs) (n = 15), and pediatric progressors (PPs) (n = 11) (see Table 1).

(B) As in (A) but showing total ILC (left), ILC1 (center left), ILC2 (center right), and ILCP (right) subset levels as percentage of CD45⁺ lymphocytes. Gating as in Figure 1A.

(C) As in (B) but showing total NK cells (left) and NK subsets (CD56^high, middle; CD16^high, right) as percentage of CD45⁺ lymphocytes.

p values by Dunn’s multiple comparisons test.