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. 2020 Apr 13;23(4):731–758. doi: 10.1111/hex.13059

TABLE 4.

Summary of citations investigating the association between psychological traits and state and increased side‐effect expectations; different studies are separated by semi‐colons

  Unadjusted Adjusted
Association Mixed association No association Association Mixed association No association
Higher health anxiety (30) study 1; (30) study 2; (50)   (28, 29) study 2; (30) study 3 (84, 85)    
Higher trait anxiety (48) study 1 (64);(89) (47);(48) study 2; (54, 55) (73)   (64)
Higher state anxiety (82) study 1   (54, 55);(86)      
Higher depression/ combined anxiety and depression score (49)   (47)     (49)
Optimism           (73);(84, 85)
Negative beliefs about medicines—overuse (49)     (49) (84, 85)  
Negative beliefs about medicines—harm     (49)   (84, 85)  
More concerns about treatment than beliefs about its necessity (49)   (48) study 1; (48) study 2     (49)
Negative beliefs about illness or pain   (49)     (83) (49)
Increased fear of intervention/distress before intervention (82) (65)   (73)    
Increased somatosensory amplification (89)   (49)      
Increased decisional conflicts about treatment (48) study 1   (48) study 2      
Style of dealing with medical information   (48) study 2 (48) study 1