Table 2.
Clinical, biological, and echocardiographic parameters of the 9 patients with treatment change induced by echocardiography.
Patients | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
---|---|---|---|---|---|---|---|---|---|
Age (years) | 56 | 54 | 82 | 76 | 64 | 74 | 62 | 59 | 66 |
Gender | M | M | F | M | F | M | M | M | F |
COVID-19 diagnosis | Chest CT | Chest CT + NP swab | Pneumonia | Chest CT + NP swab | Chest CT + NP swab | NP swab | Chest CT + NP swab | Chest CT | Chest CT |
Severity of symptoms | Intubated | Intubated | Need for oxygen | Intubated | Intubated | Intubated | Need for oxygen | Need for oxygen | Intubated |
Initial symptoms | Ischemic stroke | Resp. distress | Stroke + Resp. distress | Resp. distress | Resp. distress | Resp. distress | Resp. distress | Resp. distress | Viral syndrome |
Indication for TTE/TEE | Stroke + hemodynamic | LV function/hemodynamic | Stroke + hemodynamic | LV FP | LV FP | Hemodynamic | ACS ST- | LV function/hemodynamic | Resp. distress |
LVEF (%) | >50 | >50 | 52 | 76 | 83 | >50 | 47 | 59 | 69 |
E/Ea | 7 | NA | 16 | 9.2 | 8.5 | NA | 10.4 | 5.1 | 6.7 |
RV dilatation | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
PAPs (mmHg) | 35 | 80 | NA | 40 | 39 | 55 | NA | 42 | 38 |
Echo finding inducing the modification | Inferior wall MI | RA thrombus | RA thrombus | Not elevated LV FP | Low LV FP | Right pulmonary artery thrombus | Akinesia | Aortic aneurysm | Normal LV, low LV FP |
Treatment change | DAPT | Thrombolysis (PE) | AC | Stop diuretics | Fluid administration | NFH | DAPT | ß bloq | Stop IV nitrates |
Known CVD | No | No | Yes | Yes | No | No | No | No | No |
HTN | No | Yes | Yes | Yes | Yes | Yes | No | Yes | Yes |
Diabetes | Yes | No | No | No | No | Yes | Yes | No | No |
Body area (m2) | 2.06 | 2.35 | 1.87 | 2.19 | 1.75 | 1.97 | 1.92 | 1.83 | 1.69 |
BMI (Kg/.m2) | 29.3 | 34.0 | 26.7 | 31.3 | 34.9 | 29.6 | 27.0 | 31.2 | 29.1 |
Hs Troponin T (pg/ml) | 776,9 | 9.3 | 105.2 | 101.5 | 53.6 | 112.2 | 172.8 | 30.3 | 8.9 |
NT-pro BNP (pg/ml) | 750 | 206 | 15652 | 219 | 2808 | 6119 | 4038 | 339 | 370 |
D-dimer (ng/ml) | 20000 | 5670 | 20000 | 2690 | 1550 | 20000 | 2590 | 20000 | 20000 |
Fibrinogen (g/l) | 1.2 | 8 | 5.7 | 4.4 | 12 | 5.2 | 12 | 7.2 | 8 |
Blood type | O+ | AB+ | NA | B− | NA | O+ | O+ | O+ | A− |
Evolution# | Discharge | Still in hospital (ECMO) | Deceased | Still in hospital | Still in hospital | Still in hospital | Still in hospital | Still in hospital | Still in hospital |
Pulmonary embolism | Not assessed | Yes | No | Not assessed | No | Yes | Not assessed | No | Not assessed |
F: female; M: male; LVEF: left ventricular ejection fraction; NA: not available; RV: right ventricular; HTN: hypertension; chest CT: high CT probability of COVID-19 infection; DAPT: dual antiplatelet therapy; NP swab: positive nasopharyngeal swab; MI: myocardial infarction; PE: pulmonary embolism; AC: anticoagulant (add or modify anticoagulation regimen); RA: right atrial; Resp. distress: respiratory distress; NFH: nonfractioned heparin; CVD: cardiovascular disease; FP: filling pressures; ß bloq: beta bloquers. #Evolution: 1 discharge (to home or rehabilitation); 2 deceased; 3 still in hospital on 17/04/2020 (at the date of writing this manuscript).