Table 5.
Two-way ANOVA results for age, age of menarche, history of abortion, contraceptive drug usage, and BMI in the patient and control groups.
| Groups | Sample size | x-fold expression (vs.control groups) ± SD | p ǂ | p ¥ (tumor vs. normal) | |
|---|---|---|---|---|---|
| Control group | Cancer group | ||||
| Age | |||||
| <48 y | 18 | 18 | 1.81 ± 0.79 | Age: 0.899ǂ | 0.925 |
| ≥48 y | 18 | 18 | 1.67 ± 0.53 | BC: <0.0001ǂ | 0.873 |
|
| |||||
| Menarche age | |||||
| <13 | 9 | 13 | 1.67 ± 0.79 | Menarche: 0.741ǂ | 0.0017 |
| ≥13 | 27 | 23 | 1.75 ± 0.59 | BC: <0.0001ǂ | <0.001 |
|
| |||||
| Abortion | |||||
| Yes | 17 | 15 | 1.96 ± 0.76 | Abortion: 0.045ǂ | 0.001 |
| No | 19 | 21 | 1.84 ± 0.72 | BC: <0.0001ǂ | <0.001 |
|
| |||||
| Contraceptive drugs | |||||
| Yes | 14 | 16 | 1.74 ± 0.74 | Contraceptive drugs: 0.557ǂ | 0.004 |
| No | 22 | 20 | 1.84 ± 0.67 | BC: <0.0001ǂ | <0.001 |
|
| |||||
| Number of pregnancies | |||||
| ≤4 | 20 | 22 | 1.68 ± 0.77 | Pregnancy number: 0.266ǂ | <0.001 |
| >5 | 16 | 14 | 1.51 ± 0.23 | BC: <0.0001ǂ | <0.001 |
|
| |||||
| BMI | |||||
| BMI < 25 kg/m2 | 14 | 9 | 1.7 ± 0.33 | BMI: 0.437ǂ | 0.002 |
| 30 > BMI ≥ 25 kg/m2 | 16 | 16 | 1.8 ± 0.67 | BC: <0.0001ǂ | 0.0025 |
| BMI ≥ 30 kg/m2 | 6 | 11 | 1.97 ± 0.92 | 0.0034 | |
ǂThe two-way analysis of variance (ANOVA) was used for the comparison. ¥Tukey multiple comparison.