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Pretreatment with Mdivi-1 reversed the effect of GSC extracts against HG/PA-induced cellular senescence in HAECs. (a) Cell viability as determined by CCK-8 assay. (b) SA-β-gal were detected in HAECs. (c) Western blot analysis of p16 and p21 expression in HAECs. (d) Confocal images show γ-H2AX focus expression in HAECs. #P < 0.05 and ##P < 0.01, compared with the control group; ∗P < 0.05 and ∗∗P < 0.01, compared with the model (HG/PA) group.
