Table 2. Effects on Subjective and Objective Outcomes at Week 12 and 24 of Various Factors^a.

Variable	Pain levelb		C-Reactive protein levelc		Erythrocyte sedimentation ratec
	Week 12	Week 24	Week 12	Week 24	Week 12	Week 24
Baseline	0.6 (0.5-0.7)d	0.6 (0.5-0.7)d	−0.001 (−0.002 to −0.001)d	−0.001 (−0.002 to −0.001)d	−0.006 (−0.007 to −0.004)d	−0.005 (−0.007 to −0.002)d
Sex	0.7 (−30.5 to 50.0)	0.5 (−40.6 to 50.5)	0.101 (−0.137 to 0.340)	−0.066 (−0.432 to 0.301)	−0.081 (−0.189 to 0.026)	−0.050 (−0.183 to 0.084)
Age	0.1 (−0.1 to 0.3)	0.1 (−0.1 to 0.3)	−0.004 (−0.014 to 0.005)	−0.007 (−0.020 to 0.006)	−0.003 (−0.008 to 0.001)	−0.002 (−0.007 to 0.003)
Randomization ratio	−4.3 (−10 to 10.5)	0.5 (−120.1 to 130.1)	0.004 (−0.164 to 0.172)	0.108 (−0.076 to 0.292)	0.042 (−0.007 to 0.090)	0.025 (−0.038 to 0.089)
Washout length	−0.7 (−10.7 to 0.3)	−0.7 (−20.9 to 10.5)	0.014 (−0.014 to 0.041)	0.036 (0.009 to 0.062)d	−0.002 (−0.010 to 0.005)	0.011 (0.001 to 0.021)d

^aValues are presented as effect on the 0- to 100-mm pain scale or on the ratio outcome to baseline for C-reactive protein level and erythrocyte sedimentation rate to account for log-normal distribution.

^bPositive factors indicate improvement.

^cOwing to ratio rather than difference calculation, negative factors indicate improvement.

^dStatistically significant finding.