Table 1. Characteristics of Women With DCIS .
Variable | Women, No. (%) (N = 144 524) |
---|---|
Year of diagnosis | |
Mean (SD) [95% CI] | 2006.3 (5.2) [2006.3-2006.3] |
Median (IQR) [range] | 2007.0 (2002.0-2011.0) [1995.0-2014.0] |
1995-1999 | 15 797 (10.9) |
2000-2004 | 38 201 (26.4) |
2005-2009 | 43 426 (30.0) |
2010-2014 | 47 100 (32.6) |
Age at diagnosis, y | |
Mean (SD) [95% CI] | 57.4 (11.0) [57.4-57.5] |
Median (IQR) [range] | 57.0 (49.0-66.0) [25.0-79.0] |
<40 | 5146 (3.6) |
40-49 | 33 966 (23.5) |
50-59 | 43 737 (30.3) |
60-69 | 37 432 (25.9) |
70-79 | 24 243 (16.8) |
Race/ethnicity | |
White | 112 539 (77.9) |
Black | 15 415 (10.7) |
East Asian | 6344 (4.4) |
Southeast Asian | 5664 (3.9) |
Other or unknown | 4562 (3.2) |
Income, $ | |
Mean (SD) [95% CI] | 48 812 (11 380) [48 754-48 871] |
Median (IQR) [range] | 47 070 (42 070-55 950) [15 810-79 890] |
<40 000 | 26 729 (18.5) |
40 000-45 000 | 35 277 (24.4) |
45 000-50 000 | 23 098 (16.0) |
>50 000 | 59 407 (41.1) |
Missing | 13 (<0.1) |
Histological presentation | |
Comedonecrosis | 17 246 (11.9) |
Cribriform | 12 799 (8.9) |
Intraductal, solid type | 68 449 (47.4) |
Other ductal, NOS | 38 048 (26.3) |
Papillary | 7982 (5.5) |
Tumor grade | |
I | 16 539 (11.4) |
II | 48 852 (33.8) |
III/IV | 53 924 (37.3) |
Unknown | 25 209 (17.4) |
Tumor size, cm | |
Mean (SD) [95% CI] | 1.7 (2.1) [1.7-1.7] |
Median (IQR) [range] | 1.1 (0.6-2.0) [0.1-98.8] |
<1 | 43 152 (29.9) |
1-2 | 28 877 (20.0) |
2-3 | 12 561 (8.7) |
3-5 | 9279 (6.4) |
>5 | 6876 (4.8) |
Unknown | 43 779 (30.3) |
ER status | |
Positive | 76 611 (53.0) |
Negative | 13 730 (9.5) |
Unknown | 54 183 (37.5) |
PR status | |
Positive | 63 623 (44.0) |
Negative | 21 405 (14.8) |
Unknown | 59 496 (41.2) |
Surgical treatment | |
Lumpectomy | 96 806 (67.0) |
Mastectomy | 38 870 (26.9) |
Unknown (diagnosis prior to 1998) | 8507 (5.9) |
Unknown | 341 (0.2) |
Radiotherapy | |
No | 74 441 (51.5) |
Yes | 68 118 (47.1) |
Unknown | 1965 (1.4) |
Follow-up time, y | |
Mean (SD) [95% CI] | 9.2 (4.9) [9.1-9.2] |
Median (IQR) [range] | 8.7 (5.1-13.0) [0.1-20.0] |
Death in follow-up | |
No | 128 991 (89.3) |
Yes | 15 533 (10.7) |
Death from breast cancer | |
No | 142 984 (98.9) |
Yes | 1540 (1.1) |
Death from other cause | |
No | 130 531 (90.3) |
Yes | 13 993 (9.7) |
Vital status | |
Alive | 128 991 (89.3) |
Death from breast | 1540 (1.1) |
Death from other cancer | 3874 (2.7) |
Death from heart disease | 3880 (2.7) |
Death from other diseases | 3619 (2.5) |
Unknown cause of death | 2620 (1.8) |
Abbreviations: DCIS, ductal carcinoma in situ; ER, estrogen receptor; IQR, interquartile range; NOS, not otherwise specified; PR, progesterone receptor.