TABLE 2.

Summary of observed changes in circulating sex steroid levels in various rodent models of TLE

TLE model	Species	Estradiol	Progesterone	Testosterone
Amygdala kindling
Male	Rats	–	–	↑ Edwards et al., 1999a
Female	Rats	↑ Edwards et al., 1999c	–	–
Systemic pilocarpine
Female	Rats	↑ Amado and Cavalheiro, 1998	↓ Amado and Cavalheiro, 1998	↑ Scharfman et al., 2008
		↔ Scharfman et al., 2008	↔ Scharfman et al., 2008
Intrahippocampal KA
Male	Mice	–	–	↔ Li et al., 2018
Female	Rats	–	↓ Amado et al., 1987	–
	Mice	↑ (Estrus) Li et al., 2018	↓ (Diestrus and estrus) Li et al., 2018	–