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. 2020 Sep 7;13:3117–3135. doi: 10.2147/DMSO.S265944

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© 2020 Figueiredo et al.

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Glycoxidative stress biomarkers in kidney of streptozotocin-induced diabetic rats treated for 35 days with yoghurt enriched with lycopene, alone or in combination with metformin. Levels of TBARS (A), PCO (B), fluorescent AGEs (C). Values are expressed in terms of mean ± standard error of the mean (SEM), n = 10. Differences between groups were analyzed using one-way ANOVA followed by the Student-Newman-Keuls test (p < 0.05): ^aDifferences to NYOG; ^bDifferences to DYOG; ^cDifferences to DINS; ^dDifferences to DMET; ^eDifferences to DLYC.

Abbreviations: NYOG, normal rats treated with yoghurt; DYOG, diabetic rats treated with yoghurt; DINS, diabetic rats treated with 4U/day insulin; DMET, diabetic rats treated with 250 mg/kg metformin in yoghurt; DLYC, diabetic rats treated with 45 mg/kg lycopene in yoghurt; DML, diabetic rats treated with 250 mg/kg metformin + 45 mg/kg lycopene in yoghurt.