. 2020 Sep 7;13:3117–3135. doi: 10.2147/DMSO.S265944

Table 2.

Weights of Skeletal Muscles (Soleus, EDL) and White Adipose Tissues (Epididymal, Retroperitoneal) of Streptozotocin-Induced Diabetic Rats Treated for 35 Days with Yoghurt Enriched with Lycopene, Alone or in Combination with Metformin

	Groups
Tissues	NYOG	DYOG	DINS	DMET	DLYC	DML
Soleus muscle (g/100 g b.w.)	0.148 ± 0.011	0.119 ± 0.006^a	0.149 ± 0.004^b	0.119 ± 0.005^a,c	0.124 ± 0.006^a,c	0.130 ± 0.006^c
EDL muscle (g/100 g b.w.)	0.147 ± 0.010	0.103 ± 0.007^a	0.152 ± 0.004^b	0.109 ± 0.006^a,c	0.117 ± 0.010^a,c	0.130 ± 0.007^b,c
Epididymal adipose tissue (g/100 g b.w.)	3.750 ± 0.293	1.520 ± 0.213^a	3.470 ± 0.180^b	1.750 ± 0.254^a,c	1.740 ± 0.182^a,c	2.730 ± 0.314^a,b,c,d,e
Retroperitoneal adipose tissue (g/100 g b.w.)	3.350 ± 0.286	0.342 ± 0.105^a	3.260 ± 0.264^b	0.740 ± 0.234^a,c	0.625 ± 0.151^a,c	1.989 ± 0.306^a,b,c,d,e

Notes: Values are expressed in terms of mean ± standard error of the mean (SEM), n = 10. Differences between groups were analyzed using one-way ANOVA followed by the Student-Newman-Keuls test (p < 0.05): ^adifferences to NYOG; ^bDifferences to DYOG; ^cDifferences to DINS; ^dDifferences to DMET; ^eDifferences to DLYC.

Abbreviations: NYOG, normal rats treated with yoghurt; DYOG, diabetic rats treated with yoghurt; DINS, diabetic rats treated with 4U/day insulin; DMET, diabetic rats treated with 250 mg/kg metformin in yoghurt; DLYC, diabetic rats treated with 45 mg/kg lycopene in yoghurt; DML, diabetic rats treated with 250 mg/kg metformin + 45 mg/kg lycopene in yoghurt.