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. 2020 Sep 15;94(19):e00533-20. doi: 10.1128/JVI.00533-20

FIG 11.

FIG 11

(A to F) Assessment of drug toxicity after the administration of a combination of anti-CCR4-DT and IL-2-DT, in a ratio of 1.62:1 by weight (Combo-DT1), and in a ratio of 1:1.62 (Combo-DT2), through the dynamics of serum AST (A), ALT (B), urea (C), creatinine (D), and albumin (E). (F) Dynamics of virus reactivation in plasma (vRNA copies/ml of plasma) (F), PBMC-associated viral DNA (vDNA) copies/million cells (G), and PBMC-associated vRNA copies/million cells (H). Gray regions are normal values for chemistry parameters. The limit of detection for the plasma VL assay is 30 copies/ml.