TABLE 1.

Identification of virus (vKos_SP) haplotypes present in serum

cDNA clone	Nucleotide change (amino acid change)d						Haplotype
	T2664Ca (L764P)	A2961G (N863S)	T3735C (V1121A)	T5756C (L1795)	T6832C (S2153)	A8732G (N2787D)
Kos_SPb	+	−	−	−	−	−	II
Kos_SP 11.1c	+	−	−	−	−	−	II
Kos_SP 12.1c	+	+	+	+	+	+	I
Kos_SP 15.1c	+	−	−	−	−	−	II
Kos_SP 17.1c	+	+	+	+	+	+	I
Kos_SP 1.2c	+	+	+	+	+	−	I
Kos_SP 10.2c	+	+	+	+	+	+	I
Kos_SP 12.2c	+	+	+	+	+	+	I
Kos_SP 18.2c	+	+	+	+	+	+	I
Kos_SP 22.2c	+	−	−	−	−	−	II
Kos_SP 24.2c	+	+	+	+	+	+	I
vKos_SP inoculum	+ (>99%)	+ (54%)	+ (52%)	+ (54%)	+ (54%)	+ (54%)
vKos_SP pig 1 serum	+ (>99%)	+ (80%)	+ (78%)	+ (77%)	+ (75%)	+ (81%)

^aMutation introduced by site-directed mutagenesis.

^bBAC clone.

^cIndividual serum-derived cDNA clone.

^dA minus sign (−) indicates that the variant was not detected in the cDNA and a plus sign (+) indicates that the variant was detected.