TABLE 2.

Identification of virus (vKos_LP) haplotypes present in serum

cDNA clone	Nucleotide change (amino acid change)d						Haplotype
	G2078A (A569T)	A2380G (V669)	C2661Ta (S763L)	T2664Ca (L764P)	G3499A (G1042)	A5833G (G1820)
Kos_LPb	−	−	+	+	−	−	II
Kos_LP 12.1c	+	+	+	+	+	+	I
Kos_LP 1.2c	+	+	+	+	+	+	I
Kos_LP 5.2c	+	+	+	+	+	+	I
Kos_LP 6.2c	+	+	+	+	+	+	I
Kos_LP 8.2c	+	+	+	+	+	+	I
vKos_LP inoculum	+ (71%)	+ (69%)	+ (>99%)	+ (>99%)	+ (69%)	+ (69%)
vKos_LP pig 7 serum	+ (90%)	+ (90%)	+ (>99%)	+ (>99%)	+ (89%)	+ (89%)

^aMutation introduced by site-directed mutagenesis.

^bBAC clone.

^cIndividual serum-derived cDNA clone.

^dA minus sign (−) indicates that the variant was not detected in the cDNA and a plus sign (+) indicates that the variant was detected.