Table 2. MARK4 Inhibition and Human Cancer Cell Viability Profile of Compounds 4a–4h.
| compound | MARK4 inhibition IC50 (μM) | MCF-7 IC50 (μM) | HepG2 IC50 (μM) |
|---|---|---|---|
| 4a | >20 | 37.32 | 38.53 |
| 4b | >20 | 34.44 | 32.66 |
| 4c | >20 | 32.54 | 33.22 |
| 4d | >20 | 33.27 | 35.42 |
| 4e | 18.45 | 23.32 | 21.54 |
| 4f | >20 | 28.82 | 24.77 |
| 4g | 16.22 | 22.54 | 25.32 |
| 4h | 1.47 | 3.74 | 5.99 |