Table 1.
Plasma cytokines | TD subjects (n = 28)Mean ± SDV | ASD subjects (n = 32)Mean ± SDV | P value |
---|---|---|---|
Age (years) | 3.2 ± 0.8 | 3.1 ± 0.9 | 0.974 |
Male/Female | 16:12 | 28:4 | N/A |
IFNγ (pg/ml) | 8.61 ± 2.13 | 11.6 ± 3.11 | 0.087 |
IL-1α (pg/ml) | 21.63 ± 8.61 | 47.04 ± 12.64 | <0.01** |
IL-1Rα (pg/ml) | 87.44 ± 18.11 | 69.78 ± 21.56 | 0.416 |
IL-1β (pg/ml) | 14.73 ± 3.56 | 15.9 ± 4.12 | 0.916 |
IL-6 (pg/ml) | 12.76 ± 2.94 | 31.41 ± 5.67 | <0.01** |
IL-8 (pg/ml) | 21.36 ± 4.57 | 23.65 ± 4.19 | 0.287 |
MCP1 (pg/ml) | 36.91 ± 9.24 | 56.91 ± 10.23 | 0.036* |
MIP1α (pg/ml) | 14.23 ± 4.31 | 25.32 ± 6.27 | <0.01 |
TNF-α (pg/ml) | 15.64 ± 3.48 | 13.61 ± 2.22 | 0.798 |
ASD, autism spectrum disorders; TD, typically developing; * indicates P < 0.05; ** indicates P < 0.01.