Table 1.
Protein | Start | KBM Sequencea | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Position | |||||||||||||||||
−2 | −1 | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ||||||
hAPLF | 179 | L | A | E | R | K | R | I | L | P | T | W | M | L | A | E | H |
xAPLF | 185 | F | V | Q | R | K | R | V | L | P | D | W | M | L | H | D | D |
hMRI | 6 | S | E | T | K | T | R | V | L | P | S | W | L | T | A | Q | V |
xMRI | 31 | S | K | G | K | K | R | V | L | P | E | W | M | K | E | E | N |
WRN-NTb | 8 | T | T | A | Q | Q | R | K | C | P | E | W | M | N | V | Q | N |
xWRN-NT | 1 | M | T | S | L | Q | R | K | L | P | E | W | M | S | V | K | Q |
hWRN-CTb | 1400 | S | A | E | R | K | R | R | L | P | V | W | F | A | K | G | |
xWRN-CT | 1398 | T | T | R | P | R | R | R | L | P | E | W | Q | S | T | K | |
Fully conserved residues are underlined
WRN contains KBM sequences at both its N-terminus (NT) and C-terminus (CT)