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Effects of laquinimod on the expression of adipogenic and lipogenic genes. 3T3-L1 cells were diferentiated by incubation in cell culture medium by adding a differentiation cocktail (DMI) with laquinimod (5, 10 μM) for 3, 6, 8 days. (A) mRNA of SREBP1 as measured by real time PCR; (B) mRNA of FABP4 as measured by real time PCR; (C) mRNA of Glut4 as measured by real time PCR (****, p < 0.0001 vs vehicle group; $$, $$$$, P < 0.01, 0.0001 vs DMI treated group).
