Table 1.
Baseline table
| CMR-1 (n = 76) | CMR-2 (n = 48) | CMR-3 (n = 51) | Overall (n = 175) | |
|---|---|---|---|---|
| Age | 31 (25–42) | 30 (20–40) | 15 (11–21) | 28 (17–38) |
| Age < 18 years | 4 (5%) | 5 (10%) | 35 (69%) | 44 (25%) |
| Range | 12–68 | 16–66 | 5–64 | 5–68 |
| Male | 41 (54%) | 32 (67%) | 29 (57%) | 102 (58%) |
| Weight (kg) | 76 (65–86) | 70 (56–80) | 55 (40–70) | 69 (55–81) |
| Height (cm) | 174 (165–182) | 174 (164–182) | 162 (150–175) | 172 (159–180) |
| Body surface area (BSA) (m2) | 1.9 (1.7–2.1) | 1.8 (1.6–2.0) | 1.5 (1.3–1.9) | 1.8 (1.6–2.0) |
| Heart rate (beats/min) | 68 ± 12 | 71 ± 12 | 72 ± 13 | 70 ± 13 |
| Diagnosis | ||||
| Tetralogy of Fallot, PA + VSD | 20 (26%) | 15 (31%) | 25 (49%) | 60 (34%) |
| ASD | 2 (3%) | 1 (2%) | 5 (10%) | 8 (5%) |
| VSD | 0 (0%) | 4 (8%) | 5 (10%) | 9 (5%) |
| TGA | 6 (8%) | 5 (10%) | 2 (4%) | 13 (7%) |
| Valvular disease | 28 (37%) | 12 (25%) | 12 (24%) | 52 (30%) |
| Turner syndrome | 7 (9%) | 5 (10%) | 0 (0%) | 12 (7%) |
| Other | 4 (5%) | 5 (10%) | 2 (4%) | 11 (6%) |
| Healthy volunteer | 9 (12%) | 1 (2%) | 0 (0%) | 10 (6%) |
| Cardiac morphology & function | ||||
| Shunt lesions | 1 (1%) | 3 (6%) | 3 (6%) | 7 (4%) |
| LV ejection fraction (%)a | 55 (51–59) | 55 (47–61) | 57 (52–64) | 55 (50–61) |
| LV end-diastolic volume (ml)a | 155 (130–200) | 164 (142–199) | 144 (102–177) | 155 (124–194) |
| LV end-systolic volume (ml)a | 72 (57–89) | 76 (58–100) | 59 (40–86) | 71 (53–89) |
| RV ejection fraction (%)a | 52 (47–57) | 52 (45–56) | 53 (48–59) | 52 (47–57) |
| RV end-diastolic volume (ml)a | 190 (155–231) | 216 (174–279) | 170 (131–234) | 192 (150–248) |
| RV end-systolic volume (ml)a | 93 (67–120) | 107 (79–137) | 79 (54–117) | 95 (63–123) |
| Aortic valve | ||||
| Regurgitation | 9 (12%) | 8 (17%) | 3 (6%) | 20 (11%) |
| Stenosis | 2 (3%) | 2 (4%) | 0 (0%) | 4 (2%) |
| Bicuspid | 14 (18%) | 3 (6%) | 2 (4%) | 19 (11%) |
| Biological valve | 4 (5%) | 0 (0%) | 0 (0%) | 4 (2%) |
| Pulmonary valve | ||||
| Regurgitation | 25 (33%) | 21 (45%) | 23 (48%) | 69 (40%) |
| Stenosis | 6 (8%) | 3 (6%) | 2 (4%) | 11 (6%) |
| Biological valve | 10 (13%) | 6 (13%) | 7 (15%) | 23 (13%) |
| Vessel size | ||||
| Aorta (cm2) | 5.5 (4.3–7.7) | 5.9 (4.7–9.0) | 4.7 (3.8–6.1) | 5.3 (4.3–7.6) |
| Main pulmonary artery (cm2) | 6.2 (4.9–7.3) | 5.8 (4.7–7.5) | 4.9 (4.0–5.8) | 5.6 (4.5–7.2) |
Values are presented as numbers (percentage), mean ± SD or median (interquartile range)
ASD Atrium septal defect, AVSD Atrioventricular septal defect, PA Pulmonary atresia, TGA Transposition of the great arteries, VSD Ventricular septal defect
a Data were missing in four patients