FIGURE 1.

SHR rats have higher blood pressure but gain less weight than WKY. Systolic blood pressure over 8‐wk feeding (A) WKY vs SHR on normal chow (left) and high‐fat diet (right) or (B) effect of normal chow vs high‐fat diet on WKY (left) and SHR (right) (0 wk, n = 18; 2‐8 wk, n = 4‐6). Body weights (C) at the beginning of the study (n = 11‐12) and (D) after 8‐wk feeding (n = 5‐6), and (E) weight gain over the course of the study (n = 5‐6). Results are mean ± SEM two‐way ANOVA, t test or one‐way ANOVA; *P < .05, **P < .01, ***P < .001, ****P < .0001