Table 2.
Distributions of PFAS (ng/mL) and PBDE (ng/g lipid) concentrations in maternal serum
| MDL (ng/mL) | % Above MDL | % Machine Readable | Median | IQR (25th Percentile, 75th Percentile) | 95th Percentile | Maximum | ||
|---|---|---|---|---|---|---|---|---|
| PFAS | ||||||||
| Perfluorononanoic Acid | PFNA | 0.06 | 98.8 | 99.6 | 0.30 | (0.20, 0.44) | 0.85 | 18.7 |
| Perflucorooctane Sulfonic Acid | PFOS | 0.07 | 100.0 | 100.0 | 1.93 | (1.18, 3.13) | 6.06 | 14.5 |
| Perfluorooctanoic Acid | PFOA | 0.13 | 99.8 | 100.0 | 0.76 | (0.46, 1.12) | 2.11 | 32.2 |
| Methyl-perfluorooctane sulfonamide Acetic Acid | Me-PFOSA-AcOH | 0.01 | 98.8 | 99.8 | 0.05 | (0.03, 0.08) | 0.19 | 1.79 |
| Perfluorohexanesulphonic Acid | PFHxS | 0.01 | 100.0 | 100.0 | 0.33 | (0.20, 0.59) | 1.52 | 4.94 |
| Total PFAS > 80% MDL | 3.68 | (2.30, 5.72) | 10.2 | 54.7 | ||||
| Perfluorodecanoic Acid | PFDeA | 0.08 | 69.2 | 92.3 | 0.16 | (0.12, 0.24) | 0.50 | 3.87 |
| Perfluoroundecanoic Acid | PFUdA | 0.05 | 71.9 | 95.3 | 0.14 | (0.09, 0.23) | 0.40 | 1.26 |
| Perfluorooctane Sulfonamide | PFOSA | 0.02 | 2.37 | 42.5 | <MDL | (<MDL, <MDL) | <MDL | 0.11 |
| Perfluorobutane Sulfonate | PFBS | 0.03 | 0.79 | 52.0 | <MDL | (<MDL, <MDL) | <MDL | 0.10 |
| Perfluoroheptanoic Acid | PFHpA | 0.05 | 12.1 | 67.2 | <MDL | (<MDL, <MDL) | 0.17 | 0.49 |
| Perfluorododecanoic Acid | PFDoA | 0.20 | 2.17 | 57.9 | <MDL | (<MDL, <MDL) | <MDL | 0.48 |
| Ethyl-perfluorooctane sulfonamido Acetic Acid | Et-PFOSA-AcOH | 0.01 | 10.5 | 66.2 | <MDL | (<MDL, <MDL) | 0.05 | 0.09 |
| PBDE | ||||||||
| 2,2′,4,4′-tetra-bromodiphenyl ether | BDE-47 | 0.02 | 99.8 | 100.0 | 10.9 | (7.32, 17.0) | 39.7 | 364.3 |
| 2,2′,4,4′,5-penta-bromodiphenyl ether | BDE-99 | 0.02 | 84.4 | 99.0 | 4.1 | (2.95, 5.91) | 11.9 | 141.3 |
| Total PBDE > 80% MDL | 16.2 | (11.9, 25.6) | 54.2 | 505.6 | ||||
| 2,2′,4′-tri-bromodiphenyl ether | BDE-17 | 0.02 | 0.00 | 14.4 | <MDL | (<MDL, <MDL) | <MDL | <MDL |
| 2,4,4′-tri-bromodiphenyl ether | BDE-28 | 0.02 | 5.34 | 64.0 | <MDL | (<MDL, <MDL) | 9.00 | 15.9 |
| 2,3′,4,4′-tetra-bromodiphenyl ether | BDE-66 | 0.02 | 0.20 | 9.88 | <MDL | (<MDL, <MDL) | 4.10 | 4.10 |
| 2,2′,3,4,4′-penta-bromodiphenyl ether | BDE-85 | 0.02 | 0.99 | 11.7 | <MDL | (<MDL, <MDL) | <MDL | 12.6 |
| 2,2′,4,4′,6-penta-bromodiphenyl ether | BDE-100 | 0.03 | 44.5 | 100.0 | <MDL | (<MDL, 16.1) | 16.1 | 90.2 |
| 2,2′,4,4′,5,5′-hexa-bromodiphenyl ether | BDE-153 | 0.03 | 57.9 | 95.1 | 9.59 | (<MDL, 44.2) | 44.2 | 232.1 |
| 2,2′,4,4′,5,6′-hexa-bromodiphenyl ether | BDE-154 | 0.03 | 0.79 | 14.0 | <MDL | (<MDL, <MDL) | <MDL | 15.9 |
| 2,2′,3,4,4′,5′,6-hepta-bromodiphenyl ether | BDE-183 | 0.03 | 0.20 | 20.2 | <MDL | (<MDL, <MDL) | <MDL | 4.17 |
| 2,2′,3,3′,4,4′,5,6′-octa-bromodiphenyl ether | BDE-196 | 0.03 | 0.00 | 15.8 | <MDL | (<MDL, <MDL) | <MDL | <MDL |
| 2,2′,3,3′,4,4′,6,6′-octa-bromodiphenyl ether | BDE-197 | 0.03 | 0.99 | 43.9 | <MDL | (<MDL, <MDL) | <MDL | 23.6 |
| 2,2′,3,3′,4,5′,6,6′-octa-bromodiphenyl ether | BDE-201 | 0.03 | 0.00 | 16.8 | <MDL | (<MDL, <MDL) | <MDL | <MDL |
| 2,2′,3,3′,5,5′,6,6′-octa-bromodiphenyl ether | BDE-202 | 0.03 | 0.00 | 12.7 | <MDL | (<MDL, <MDL) | <MDL | <MDL |
| 2,2′,3,4,4′,5,5′,6-octa-bromodiphenyl ether | BDE-203 | 0.03 | 0.00 | 13.0 | <MDL | (<MDL, <MDL) | <MDL | <MDL |
| 2,2′,3,3′,4,4′,5,5′,6-nona-bromodiphenyl ether | BDE-206 | 0.04 | 0.00 | 15.8 | <MDL | (<MDL, <MDL) | <MDL | <MDL |
| 2,2′,3,3′,4,4′,5,6,6′-nona-bromodiphenyl ether | BDE-207 | 0.04 | 0.79 | 53.6 | <MDL | (<MDL, <MDL) | <MDL | 13.1 |
| 2,2′,3,3′,4,5,5′,6,6′-nona-bromodiphenyl ether | BDE-208 | 0.04 | 0.00 | 27.5 | <MDL | (<MDL, <MDL) | <MDL | <MDL |
| 2,2′,3,3′,4,4′,5,5′,6,6′-deca-bromodiphenyl ether | BDE-209 | 0.14 | 2.77 | 58.1 | <MDL | (<MDL, <MDL) | <MDL | 75.5 |
Abbreviations: PFAS per- and polyfluoroalkyl substances, PBDE polybrominated diphenyl ethers, MDL method detection limit, IQR interquartile range
Note: % machine readable indicates the percent of PFAS and PBDE concentrations in which a signal was obtained. Median, IQR, 95th Percentile, and Maximum values were calculated with PFAS and PBDE concentrations below the MDL coded as missing