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. 2020 Jul 30;85(2):239–243. doi: 10.1097/QAI.0000000000002452

TABLE 2.

Comparison of Clinical Outcomes Between the Control Group and the Treatment Group

Clinical Outcomes Total (n = 129) Control Group (n = 59) Lopinavir/Ritonavir Group (n = 51) Chloroquine Group (n = 19) Control vs Lopinavir/Ritonavir Control vs Chloroquine
P1 OR1 (95% CI) P2 OR2 (95% CI)
Fever duration, median (range), d 8 (5–10), n = 89 8 (6–11), n = 44 7.5 (4.8–9.3), n = 38 6 (4–9), n = 7 0.146 0.910 (0.802 to 1.033) 0.690 0.958 (0.778 to 1.181)
Time from illness onset to, median (range), d
 Chest CT improvement 15 (13–19.3), n = 114 15.5 (11–20.8), n = 52 13 (15–19), n = 47 14 (12–20), n = 15 0.949 1.003 (0.92 to 1.084) 0.770 0.984 (0.886 to 1.093)
 Negative nucleic acid conversion 23 (15–33.8), n = 119 21 (15–28.8), n = 59 23 (17–35.5), n = 45 16 (14–41), n = 15 0.285 1.018 (0.985 to 1.051) 0.839 1.004 (0.963–1.047)
Severe cases, n (%) 6 (4.7) 2 (3.4) 3 (5.9) 1 (5.3) 0.882 1.163 (0.158 to 8.568) 0.714 1.583 (0.136 to 18.5)
Changes of Ct value from day 1 to day 7, median (range)
 N gene 9.0 (3.9–13.3), n = 44 5 (2–11), n = 19 7 (5.0–12.5), n = 13 8.0 (6.6–20.8), n = 12 0.228 0.918 (0.800 to 1.055) 0.055 0.895 (0.798 to 1.002)
 ORF1ab gene 8.9 (3.0–13.4), n = 44 4 (2–8), n = 19 8.5 (5.4–13.5), n = 13 7.6 (4.5–21), n = 12 0.172 0.916 (0.808 to 1.039) 0.077 0.920 (0.838 to 1.009)