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. 2020 Jul 9;31(7):240–251. doi: 10.1007/s00335-020-09844-2

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Sequence logos obtained from 40-nt promoter sequences. Human, macaque, and mouse logos are displayed from left to right. Transcription start sites (TSSs) are located at position 0, which corresponds to the traditional + 1 start site. a TSSs were inferred from 5ʹ end of RefSeq entries. Promoter elements are not clear in all the three species. b Human representative TSSs were obtained from DBTSS. The Inr or YR consensus dinucleotide is evident. Disappearance of G and C nucleotides around position -27 suggests presence of TATA boxes. Macaque and mouse TSSs were inferred from sequence alignments against human TSSs