Table 3.

Intratumoral gene expression by treatment

	Prior treatment		Posttreatment		Change (post-prior)
Gene	n	Median (min–max)	n	Median (min–max)	n	Median (min–max)	Pa
TS	38	3.16 (0.53–9.57)	39	3.64 (0.67–11.30)	34	0.38 (−2.33–7.25)	0.10
DPD	32	0.58 (0.14–1.87)	33	0.68 (0.16–2.71)	26	0.12 (−0.61–1.04)	0.097
EGFR/HER1	37	1.59 (0.51–87.84)	37	1.73 (0.10–89.64)	32	0.15 (−1.88–41.89)	0.10
HER2	33	0.04 (0.01–0.49)	34	0.06 (0.01–1.87)	28	0.01 (−0.29–1.61)	0.26
HER3	37	4.51 (1.25–43.61)	40	6.18 (0.89–12.86)	33	0.87 (−36.31–8.18)	0.38

^aBased on the Wilcoxon signed rank test.