Table 2.

Baseline characteristics

Characteristics	Minocycline 1% (n = 92)	Minocycline 3% (n = 96)	Vehicle (n = 82)	Overall (n = 270)
Nodules
Mean ± SD	0·2 ± 0·6	0·2 ± 0·6	0·2 ± 0·5	0·2 ± 0·8
Range	0–4	0–3	0–3	0–8
Papules
Mean ± SD	20·8 ± 7·9	21·5 ± 7·9	20·8 ± 7·9	21·0 ± 7·9
Range	0–39	6–40	9–40	0–40
Pustules
Mean ± SD	3·8 ± 6·2	3·7 ± 5·1	3·5 ± 4·1	3·7 ± 5·2
Range	0–38	0–33	0–18	0–38
Total inflammatory lesion count (papules and pustules)
Mean ± SD	24·6 ± 7·4	25·1 ± 7·9	24·3 ± 8·2	24·7 ± 7·8
Range	12–40	12–40	12–40	12–40
Investigator's Global Assessment  score
0 (clear), n (%)	0 (0)	0 (0)	0 (0)	0 (0)
1 (almost clear), n (%)	0 (0)	0 (0)	0 (0)	0 (0)
2 (mild), n (%)	7 (8)	3 (3)	6 (7)	16 (6)
3 (moderate), n (%)	75 (81)	80 (83)	69 (84)	224 (83)
4 (severe), n (%)	10 (11)	13 (13)	7 (9)	30 (11)
Investigator's Global Assessment score including erythema
0 (clear), n (%)	0 (0)	0 (0)	0 (0)	0 (0)
1 (almost clear), n (%)	0 (0)	0 (0)	0 (0)	0 (0)
2 (mild), n (%)	0 (0)	0 (0)	0 (0)	0 (0)
3 (moderate), n (%)	85 (92)	86 (90)	74 (90)	245 (91)
4 (severe), n (%)	7 (8)	10 (10)	8 (10)	25 (9)