Table 1.
Baseline Demographics, Headache Characteristics, and Depression† and/or Anxiety‡ for All Respondents with Migraine
| Characteristic | Respondents (N = 16,788)§ |
|---|---|
| Age, years, mean (SD) | 41 (14) |
| Women, n (%) | 12,494 (74.4) |
| Race,¶ n (%) | |
| White | 13,562 (81.1) |
| Black | 1540 (9.2) |
| Other | 1106 (6.6) |
| Multiracial | 518 (3.1) |
| Annual household income,¶ n (%) | |
| <$30,000 | 3741 (22.5) |
| $30,000‐$49,999 | 2990 (17.9) |
| $50,000‐$74,999 | 3774 (22.6) |
| ≥$75,000 | 6158 (37.0) |
| BMI, kg/m2, mean (SD) | 28.7 (7.6) |
| Cutaneous allodynia, ASC‐12 ≥3,¶ n (%) | 5820 (45.4) |
| MSSS, mean (SD) | 22.4 (3.2) |
| MIDAS score grade III/IV, n (%) | 6539 (39.0) |
| Monthly headache‐day frequency | |
| Days/month, mean (SD) | 5.0 (6.0) |
| Category, n (%) | |
| 0‐4 days/month | 11,159 (66.5) |
| 5‐9 days/month | 2904 (17.3) |
| 10‐14 days/month | 1249 (7.4) |
| ≥15 days/month | 1476 (8.8) |
| Depression† | 5425 (32.3) |
| Anxiety‡ | 5022 (29.9) |
| Psychiatric subgroups, n (%) | |
| Depression only | 1613 (9.6) |
| Anxiety only | 1210 (7.2) |
| Depression and anxiety | 3812 (22.7) |
| Neither depression nor anxiety | 10,153 (60.5) |
Depression was defined as 9‐item Patient Health Questionnaire score ≥10.
Anxiety was defined as 7‐item Generalized Anxiety Disorder Scale score ≥10.
Subsample that completed Endophenotype Module and who were included in the final model. Note: There was one person with missing data for the anxiety and depression measures, so the sample size for this study differs by n = 1 from the total CaMEO baseline sample.
Results were not provided by all respondents; percentages are reported as the percentage of respondents for each data point.
ASC‐12 = 12‐item Allodynia Symptom Checklist; BMI = body mass index; CM = chronic migraine; EM = episodic migraine; MIDAS = Migraine Disability Assessment Scale; MSSS = Migraine Symptom Severity Score.