Table 4.
Median OS (Months) According to the Risk Categories
| Figure | Risk Stratification | Risk Category | N | Median OS (95% CI) | Hazard Ratio (95% CI) | P Value |
|---|---|---|---|---|---|---|
| 1A Derivation set | Pre‐TACE‐Predict model | 1 | 233 | 41.02 (36.84, 49.24) | 1 | |
| 2 | 496 | 29.18 (27.20, 33.49) | 1.57 (1.27, 1.95) | <0.0001 | ||
| 3 | 495 | 17.99 (16.81, 19.93) | 2.59 (2.10, 3.20) | <0.0001 | ||
| 4 | 231 | 8.36 (6.84, 9.77) | 5.44 (4.31, 6.86) | <0.0001 | ||
| 1B Internal validation set | Pre‐TACE‐Predict model | 1 | 255 | 39.18 (34.44, 51.77) | 1 | |
| 2 | 483 | 25.89 (23.09, 27.89) | 1.58 (1.29, 1.93) | <0.0001 | ||
| 3 | 499 | 18.22 (15.99, 20.23) | 2.26 (1.86, 2.75) | <0.0001 | ||
| 4 | 219 | 8.65 (7.73, 9.97) | 3.93 (3.15, 4.90) | <0.0001 | ||
| 1C External validation set (Eastern) | Pre‐TACE‐Predict model | 1 | 44 | 46.68 (29.05, 54.05) | 1 | |
| 2 | 124 | 33.82 (28.68, 42.66) | 1.36 (0.85, 2.19) | 0.201 | ||
| 3 | 228 | 16.88 (14.11, 19.34) | 2.66 (1.71, 4.15) | <0.0001 | ||
| 4 | 330 | 7.93 (6.94, 9.08) | 4.94 (3.19, 7.65) | <0.0001 | ||
| 1D External validation set (Western) | Pre‐TACE‐Predict model | 1 | 40 | 34.77 (26.81, 47.24) | 1 | |
| 2 | 96 | 23.95 (19.64, 30.69) | 1.33 (0.89, 1.98) | 0.165 | ||
| 3 | 155 | 17.11 (12.63, 22.50) | 1.74 (1.19, 2.53) | 0.004 | ||
| 4 | 73 | 8.29 (6.28, 12.27) | 2.99 (1.97, 4.53) | 0.0001 | ||
| 2 All patients | mRECIST | CR | 625 | 42.83 (38.83, 46.68) | 1 | |
| PR | 745 | 22.70 (21.09, 24.21) | 1.99 (1.71, 2.31) | <0.0001 | ||
| SD | 765 | 14.28 (13.03, 15.76) | 2.95 (2.56, 3.40) | <0.0001 | ||
| PD | 496 | 8.85 (7.87, 10.13) | 4.51 (3.87, 5.26) | <0.0001 | ||
| 3A Derivation set | Post‐TACE‐Predict model | 1 | 101 | 55.53 (47.53, NR) | 1 | |
| 2 | 218 | 30.26 (26.05, 34.61) | 2.50 (1.68, 3.72) | <0.0001 | ||
| 3 | 214 | 17.93 (15.26, 20.46) | 5.03 (3.40, 7.42) | <0.0001 | ||
| 4 | 92 | 8.36 (6.88, 9.34) | 12.35 (8.06, 18.93) | <0.0001 | ||
| 3B Internal validation set | Post‐TACE‐Predict model | 1 | 106 | 51.18 (37.37, 78.22) | 1 | |
| 2 | 221 | 27.50 (24.97, 35.76) | 2.14 (1.48, 3.08) | <0.0001 | ||
| 3 | 220 | 19.47 (16.51, 24.21) | 3.37 (2.36, 4.80) | <0.0001 | ||
| 4 | 79 | 8.09 (5.72, 10.53) | 7.55 (5.01, 11.39) | <0.0001 | ||
| 3C External validation set (Eastern) | Post‐TACE‐Predict model | 1 | 38 | 49.80 (28.06, 70.03) | 1 | |
| 2 | 99 | 31.22 (27.53, 37.53) | 1.72 (1.02, 2.90) | 0.043 | ||
| 3 | 203 | 21.18 (17.60, 24.97) | 2.39 (1.46, 3.92) | 0.001 | ||
| 4 | 375 | 7.01 (6.09, 7.80) | 5.94 (3.68, 9.59) | <0.0001 | ||
| 3D External validation set (Western) | Post‐TACE‐Predict model | 1 | 9 | 25.13 (11.68, NR) | 1 | |
| 2 | 41 | 34.31 (23.39, 47.11) | 1.44 (0.57, 3.67) | 0.444 | ||
| 3 | 147 | 22.96 (18.78, 27.34) | 1.81 (0.74, 4.44) | 0.192 | ||
| 4 | 144 | 9.84 (6.35, 11.78) | 3.50 (1.43, 8.56) | 0.006 |