Table 5.

Number of therapeutic interventions applied for retinal haemangioblastomas in patients with von Hippel–Lindau disease.

	Interventions per patient in missense group (n = 6)	Interventions per patient in truncating group (n = 14)	p
Therapeutic interventions, mean (range)	10.5 (3–22)	7.7 (1–46)	0.080
Laser	4.7 (2–11)	6.0 (1–29)	0.267
Cryocoagulation	1.2 (0–3)	0.7 (0–5)	0.381
Vitreoretinal surgery	2.7 (0–7)	0.9 (0–8)	0.036
Photodynamic therapy	0.5 (0–2)	0.0 (0–0)	0.267
Anti‐VEGF	1.5 (0–6)	0.6 (0–5)	0.302
Radiation therapy (Ruthenium‐106 brachytherapy)	0 (0–0)	1 (0–1)	0.850

VEGF = Vascular Endothelial Growth factor.

The bold values are considered statistically significant.